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Steroids are synthetic compounds similar in structure and properties to the male sex hormones (androgens). Androgens are characterized by anabolic activity, characterized by the acceleration of the processes of synthesis, the formation of substances of all classes in the body.
Anabolic steroids are used in medical practice in the treatment of serious diseases, in sports to increase testosterone levels, increase muscle mass.
Long-term, as well as uncontrolled intake of steroids adversely affect the liver, cardiovascular system, organs of reproduction, the state of mind.
On the liver
Taking steroids can lead to a malignant liver tumor. The risk of adverse effects is enhanced when taking drugs in pills. The effect of drugs on the liver is not always manifested by changes in blood levels, they can go unnoticed for a long time.
Action on the heart and blood vessels
The effect of steroids on the heart and blood vesselsAcceptance of anabolic steroids affects the ratio of high and low density cholesterol, increases the amount of total cholesterol.
These changes cause the formation of cholesterol plaques, the narrowing of the lumen of blood vessels, contributes to the appearance of:
- water retention in the body;
- weight gain;
- high pressure;
- heart attack.
On the sexual system
Prolonged uncontrolled use of steroids can cause hormonal imbalance in men and women. In women, the drug reduces the level of the hormones that regulate the menstrual cycle, which are responsible for the maturation of the egg and ovulation.
The presence of male hormones in the body causes:
- male-type hair growth;
- low tone of voice;
- hair loss;
- decrease in mammary glands;
- increase in the size of the clitoris.
For men, the reception of anabolic steroids turns into feminization, the formation of the body according to the female type. The increase in testosterone concentration caused by taking steroids, inhibits the production of testosterone, negatively affects the quality of sperm, the viability of sperm.
In the semen, the number of damaged sperm cells increases, and fertility decreases. A feature of steroid metabolism in men is their transformation into female sex hormones – estradiol, estrone. Estrogens stimulate the growth of the mammary glands, causing irreversible changes. There are even cases of lactation.
On the psyche
The use of steroids causes a change in the psyche. In individuals taking anabolic steroids, the character changes:
- increased aggressiveness;
- excitability increases;
- there is a sleep disorder.
Steroid drugs have the ability to suppress immunity, which increases the risk of cancer.
After reviewing the side effects of steroids, you can get an idea of the opposite effect of steroids and alcohol. Alcohol lowers testosterone levels, inhibits growth hormone secretion, promotes fat accumulation, significantly increasing cortisol synthesis.
In addition, alcohol enhances the harm of steroids caused by side effects of taking.
The main destructive effect of ethanol on the cycle of steroids has on the liver. In this body, the metabolism and ethyl alcohol, and steroids. The enzyme system of the body is double the load, causing metabolic disorders in general.
Thus, under the influence of ethanol, fat metabolism is disturbed. The rate of fat oxidation is reduced by 70%. Under the influence of alcohol, the production of protein is reduced, the activity of growth factors is inhibited – somatomedin C, somatotropic hormone.
Such an effect of alcohol inhibits the synthesis process, which is the opposite of the expected effect of the use of anabolic steroids – the acceleration of protein synthesis.
It should be noted here that in insignificant concentration ethyl alcohol has an anabolic effect, but this dose for men does not exceed 25 ml of alcohol, i.e. no more than 100 ml of vodka or 200 ml of wine. And no more than 1-2 times in 8 days.
In reality, these conditions are not maintained, and alcohol fully exhibits its destructive properties that enhance catabolism – the inhibition of synthesis processes in the body.
Impact on the psyche
The impact of alcohol and anabolic steroids on the psyche. The intake of steroid drugs in dosages exceeding therapeutic, as well as individuals with an unstable psyche, may be accompanied by increased aggressiveness, the so-called “steroid rage.”
In a mentally stable person, taking steroids increases testosterone levels, but does not cause uncontrolled aggression. Another thing – a mentally unstable person, or a person who has consumed alcohol during treatment with anabolic drugs.
Alcohol inhibits the activity of the cortex, reduces the level of control over conscious activity. And it disinhibits the work of brain centers responsible for basic instincts, assessing the level of danger, threats from the outside world.
When intoxicated, even if a small dose is drunk, it is difficult to control the behavior, and any glance can cause an outbreak of anger.
Changes in water-salt balance
Ethanol has a diuretic effect, greatly dehydrates the body. Steroids cause edema and fluid retention. This leads to an imbalance in the content of electrolytes, violation of vital indicators, such as blood viscosity.
Effects of combining
The effects of alcohol during the cycle of steroids appear:
- liver damage with a confirmed increase in liver enzyme concentration, transient jaundice, impaired bile outflow;
- the occurrence of cholestatic hepatitis when taking anabolic steroids containing a group of 17-alpha hydroxylase,
- increased blood pressure caused by dehydration as a result of disruption of water-salt balance;
- increased blood viscosity by increasing cholesterol;
- hormonal imbalance in men and women;
- a violation of spermatogenesis, a decrease in the number of spermatozoa in the ejaculate in men;
After a cycle of steroids, alcohol is allowed no earlier than after 3 weeks. If an important event is to be held, and there is no way to completely give up alcohol, then during the cycle of steroids, alcohol can be taken in a dose of not more than 100 g of vodka or 200 g of wine no more than after 4 days.
At this dose and with such a frequency of administration to healthy people, ethyl alcohol has an anabolic effect, stimulating the processes of synthesis in the body, similar to the action of anabolic steroid drugs.